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139 WilsonH

Chui CS, Mohan R

doi:10.23750/abm.v90i3-S.8159 3Holland KE, Soung PJ

More importantly, after long-term CCl4 treatment in Nrf2 gene knockout mice, liver fibrosis was severely intensified, and inflammation increased (Xu et al., 2008)

DEM has been reported to produce a non-linear response to glutathione depletion, with a minor glutathione loss induced by DEM at 10100 M increasing lifespan via hormesis, but a major glutathione loss induced by DEM 1 mM shortening lifespan (Urban et al., 2017)