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FtH-Mediated ROS Dysregulation Promotes CXCL12/CXCR4 Axis Activation and EMT-Like Trans-Differentiation in Erythroleukemia K562 Cells

207 NF-B-binding sites have been identified in the Beclin 1 promoter, indicating direct transcriptional control by NF-B in multiple cell types

We showed that mice fed a high-fat diet (HFD) for 12 weeks developed hepatic steatosis and liver injuries, which were associated with not only TNF overproduction but also hepatic glutathione dysregulation, characterized by GSH reduction and GSSG elevation

6:e28083 10.7554/eLife.28083 [DOI] [PMC free article] [PubMed] [Google Scholar] Shi Z.-Z., Habib G.M., Rhead W.J., Gahl W.A., He X., Sazer S., and Lieberman M.W

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