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In conclusion, these results indicate that VPA-exposed rats avoided social interaction and preferred non-social contexts, reflecting impaired sociability (P 0.05 )

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To complete the synthesis of di- tert -butyl ester of (2 R ,3 S )- 2 compound 16 was first transformed into the ester and later deprotected to the diol 17 which was selectively oxidized, again esterified and finally the phenylsulfonyl group was removed electrochemically (Scheme 4) [52]

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