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Given the thin evidence base and the absence of large controlled trials, caution is warranted, and consultation with a qualified physician is strongly recommended

Combined serum neurofilament light chain and Tau as biomarkers of diabetic peripheral neuropathy

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-syn aggregation leads to increased iron deposition and ferroptosis in PD mice, while MT1 knockout reduces the resistance of neurons to ferroptosis by inhibiting the SIRT1/Nrf2/HO-1/GPX4 pathway and inhibiting the expression of ferritin FTH1, resulting in more ferrous ion release, which further leads to more DA neuron loss and severe dyskinesia

Do not use on wounded, cracked, irritated, or highly sensitive skin