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For its second application, the FDA set a PDUFA date of May 14, 2024, but this was pushed back by three months after Ascendis filed a major amendment to the application

Hospitals rely on IV fluids for dehydration , IV iron for anemia , and B12 injections for deficiency where oral supplements are not effective

Further, increased expressions of liver PPAR- (peroxisome proliferator-activated receptors), which plays a vital role in decreasing triglycerides [57]

However, the more recent DRIVE trial showed that patients with ferritin levels of 500 to 1,200 ng/mL will respond to intravenous administration of iron with an increase in their hemoglobin levels

Treatment Improving symptoms and preventing organ damage are the main aims of treatment for WD