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Tesamorelins pivotal trials tested reduction of excess visceral (abdominal) fat in people with HIV-associated lipodystrophy, and that is its FDA-approved indication

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As per the researchers, Tesamorelin is a synthetic growth hormone-releasing hormone that acts on the anterior pituitary gland to stimulate the endogenous growth hormone secretion. (6) Studies suggest that the peptide may potentially cause a 69% increase in total growth hormone levels (apparently assessed via area under the curve - AUC) and a purported 55% increase in the mean pulse area of the growth hormone