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B12 deficiency may be caused by lack of a protein called intrinsic factor

[12:42] If you add to that that the microglia also influence quinolinic acid, serotonin, dopamine, and a host of other neurochemical pathways that then influence the neuroexcitatory sympathetic response, you've got sensory overwhelm, everything in the world seems disproportionately threatening, and you're hyper-alert

Evidence for noncanonical neurotransmitter activation: norepinephrine as a dopamine D 2 -like receptor agonist

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