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Things that might lead to dose changes include how bad the deficiency was, if there are nerve symptoms, if theres ongoing trouble absorbing nutrients, and how each patient responds

Revollo JR, Grimm AA, Imai SI (2004) The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

If you follow a vegan diet, lack B12-rich food, or suffer from health conditions like B12 deficiency, which happens when a person cannot absorb it properly, then you may experience b12 deficiency

Emma M., review from WhatClinic Please note that results vary from person to person due to lifestyle, external and internal factors, and genetic predispositions