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When you eat the fish in its whole form, you get all of the protein, which is the most satiating part, and the micronutrients from the bones.

The review points to DNA-repair decline, oxidative stress, senescence-associated processes, altered signaling, and the follicle niche itself

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Exp Neurobiol 22:1117 Markesbery WR (1997) Oxidative stress hypothesis in Alzheimer's disease

Managing side effects often involves lifestyle adjustments and communication with healthcare providers