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& Nakov, L

doi: 10.3390/antiox11091811 223 ZhengX.WuX.WenQ.TangH.ZhaoL.ShiF.et al

It acts as a coenzyme in the mitochondria the powerhouses of the cell where it helps convert glucose into ATP, the cells usable form of energy

revealed that overexpression of GPX4 inhibits IL-6-induced activation of the JAK1/STAT3 signaling pathway in VSMCs, thereby reducing the recruitment and polarization of pro-inflammatory macrophages