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Along with infiltration by inflammatory cells, it also causes dysfunction of the glomerular filtration barrier, and therefore albuminuria (81)

Previous studies have demonstrated that the use of RXR partial agonists can reduce eosinophilic airway inflammation, a condition mediated, in part, by the chemoattractant activity of CCL11 60

This may involve: Ensuring the water dish is always full of fresh, clean water to promote drinking Adding water to dry food Feeding canned food since it is about 75-80% water Sometimes these measures can be sufficient in the early stages of kidney disease in dogs or for other minor issues

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