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An inhibitory study revealed that the inhibition of cysteine uptake by MeHg in astrocytes occurs through a Na + -independent ASC system that is responsible for the transport of small amino acids and the Na + - and K + -dependent amino acid transport system X-AG

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These results reveal that the modified method can provide reliable and comparable measurements of GPx activity, making it a viable alternative to the established reference protocol

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Su9Grx1roGFP2 also localized to the mitochondrial fraction but was only protease accessible in completely lysed mitochondria and not in intact mitochondria or in mitoplasts (Figure 2A, bottom , lane 6), therefore indicating its matrix localization

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248 Although such a feature could be explained by an ACP transferase catalyzed reaction in the biosynthetic pathway as described in Section 2.1.1 followed by decarboxylation, no ACP transferase or SAM methyltransferase homolog is conserved among the biosynthetic gene clusters for muraymycins or related compounds

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