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Description

Clomiphene citrate as nanomedicine assistance in ovulatory disorders and its hyphenated techniques

gentle agitation is sufficient for complete dissolution

Most preclinical studies utilize supraphysiologic doses, alternate routes of administration and short follow-up windows that do not mimic human reproductive timelines

Both subcutaneous and intramuscular administrations are common in preclinical studies

Le Loir Y, Azevedo V, Oliveira SC, Freitas DA, Miyoshi A, Bermudez-Humaran LG, Nouaille S, Ribeiro LA, Leclercq S, Gabriel JE, Guimaraes VD, Oliveira MN, Charlier C, Gautier M, Langella P (2005) Protein secretion in Lactococcus lactis : an efficient way to increase the overall heterologous protein production