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Aflatoxin contamination in corn-based pet foods has caused documented mass fatality events in dogs, with multiple FDA-reported outbreaks over the past two decades (PFI 2011, FDA 2021)

NAD(P)H has also been identified as a protective agent, scavenging the deaminated filters (109)

EX527 reverses the anti-inflammatory and anti-apoptotic effects of NMN on BEAS-2B cells To further confirm that the protective effects of NMN are associated with SIRT1, we used EX-527, a selective inhibitor of SIRT1, to block the SIRT1 pathway in NMN-treated BEAS-2B cells