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SKU: 20373683531
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2.5 Molecular dynamics The protein complexes formed with DSF and the standard drug underwent all-atom explicit molecular dynamics (MD) simulations for 100 ns in an explicit solvent using the ff99SBildn force field in xleap tool of Amber antechamber (Wang et al., 2001) with GROMACS software (Lindahl et al., 2001)

128,129 The anti-inflammatory effects of corticosteroids are mediated by GR, and functional impairment of GR is an important mechanism of glucocorticoid resistance