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The primary reason is that the medications influence many of the same biological systems

showed a reversal of steatohepatitis in female mice by resulting in enhanced glucose tolerance, decreased body weight and fat mass, and better lipid profiles, thereby aiding in the resolution of hepatic steatosis [42]

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CagriSema: Combination Therapy Program CagriSema is a fixed-ratio combination of cagrilintide (amylin analogue) and semaglutide 2.4 mg (GLP-1 receptor agonist), designed to provide superior weight loss through complementary mechanisms of action