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A molecular perspective on age-dependent changes to the heat shock axis

Berg and Shaw presented a cascade-testing algorithm that stratified patients first by total serum vitamin B 12 levels and second by MMA levels, using cutoffs of 118 pmol/L and 0.80 mol/L, respectively (Berg and Shaw, 2013)

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Multicomponent exercise not only improves physical fitnessincluding scores on the Short Physical Performance Battery (SPPB), a popular scale for measuring frailtybut also improves cognitive function after 24 months of exercise in older patients with diabetes and impaired lower-limb function [235]