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A phase 2b randomized trial of lorecivivint, a novel intra-articular CLK2/DYRK1A inhibitor and Wnt pathway modulator for knee osteoarthritis

The authors declare that the data supporting the findings of this study are available within the paper and its extended data files

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We immunized K18-hACE2 transgenic mice, and hamsters with pCTV-WS and evaluated humoral and cellular immune responses by analyzing neutralizing and non-neutralizing antibodies levels, frequency of immune cells and cytokine and chemokine levels in lung tissue