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Glutathione metabolism functions in antioxidant defense, signal transduction, cytokine production, and other cellular processes such as detoxification

NAC replenishes glutathione, a critical antioxidant that protects neurons from oxidative stress post-injury

While many small molecules have been developed to target RNA structures 1 , most studies have focused on interactions with reference genomes, overlooking the potential influence of genetic variation

Shaito et al., 2022)

In FoB, we found that ATP levels in Gclc -deficient, but not in Gclc -sufficient FoB dropped in a dose-dependent fashion in response to inhibition of glycolysis with 2-deoxy-D-glucose (2-DG) or galactose (Fig