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doi: 10.3390/molecules24203693, Summary Keywords food-derived compounds, ischemic stroke, molecular mechanisms, natural bioactive compounds, therapeutic interventions Citation Bu F, Zhang Z, Qi S and Xu L (2026) From diet to brain repair: natural bioactive compounds in post-ischemic stroke recovery

Sci Rep 16 , 11418 (2026)

In a non-cancer context, it is known that hypoxia links erythropoiesis with iron homeostasis and that the hepcidin/FPN1 axis regulates intestinal HIF2 to modulate iron absorption, through transcriptional activation of DMT1 , DCYTB , and FPN1 [118,119,120]

[DOI] [PubMed] [Google Scholar] 315.Radomska D., Czarnomysy R., Radomski D., Bielawski K

Based on studies carried out on murine models, the authors hypothesised that the milk pro-oxidant galactose (component of lactose) may be one of the main causes of these observed effects ( Reference Cui, Zuo and Zhang 116 Reference Hao, Huang and Gao 118 ) , with the increase in oxidative stress specifically associated with a lower life expectancy in animals ( Reference Cui, Wang and Zuo 119 ) and with chronic diseases in humans ( Reference Utkualp and Ozdemir 120 , Reference Moylan and Reid 121 )