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However, active absorption may be more efficient when supplementing with either small or high B12 doses

3: moderate generalized irregularity of the diameter of blood vessels with moderate atrophy of the optic disc, barely visible (faint presentation) choroidal blood vessels (brighter fundus background color)

Ethics declarations Ethics approval and consent to participate The experimental protocol was developed according to the ethical principles enshrined in the Declaration of Helsinki (2013 amendment) and approved by the Ethics Committee at The 908th Hospital of Chinese Peoples Liberation Army Joint Logistic Support