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Promoting Long-Term Vitality: Our organs are vital to our overall health and vitality

Mitochondrial damage was observed in the GOx/CuSAE-treated cells with a decrease of polarized membrane and an increase of depolarized membrane, detected using a mitochondrial membrane potential probe JC-1, which showed green fluorescence in monomer form (J-monomer) in damaged mitochondria and red fluorescence in aggregate (J-aggregates) in normal mitochondria (Fig

Collectively, these results demonstrated that clofazimine exerts antiviral activity by targeting several steps in SARS-CoV-2 replication, including interference with S-mediated cell fusion as well as viral helicase activity