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Ghrelin and ghrelin receptor agonists stimulate gastrointestinal motility through vagal afferent pathways and direct effects on enteric neurons

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Moreover, a healthy diet, including one rich in fruits and vegetables and low in fat, has been shown to be associated with less ED in the general population [165], and the potential of plant-based diets in MetS-associated ED was also highlighted [166]

Furthermore, the stool provides non-invasive but limited insight into the gut microbial community