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Similarly, HHcy induced by either a folate-deficient diet or by directly infusing Hcy into the mouse brain worsens the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mediated PD symptoms such as dopamine depletion, substantia nigra pars compacta neuronal degeneration and motor dysfunction [82]

3.3 Ferroptosis Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, may play a key role in the pathogenesis of PCOS

Jelinek J, Kroeger H, He R, Saraf A, Lau SM, T-V N, Thomas MW, Shpall EJ, Kornblau SM , Bueso-Ramos C, Kantarjian HM, Issa JP

Nanosystems in cardiovascular medicine: advancements, applications, and future perspectives

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