glutathione in ovarian cancer a double-edged sword

glutathione in ovarian cancer a double-edged sword responsive nanomedicine leverages tumor redox imbalance for targeted theranostics | Discover Oncology Living on the Edge: ROS

Name: glutathione in ovarian cancer a double-edged sword responsive nanomedicine leverages tumor redox imbalance for targeted theranostics | Discover Oncology Living on the Edge: ROS
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Living on the Edge: ROS Homeostasis in Cancer Cells and Its Potential as a Therapeutic Target PMC Targeting ferroptosis in ovarian cancer: Novel strategies to overcome chemotherapy resistance ScienceDirect Redox Regulated Iron Metabolism and Ferroptosis in Ovarian Cancer: Molecular Insights and Therapeutic Opportunities Ferroptosis in epithelial ovarian cancer: a burgeoning target with extraordinary therapeutic potential Cell Death Discovery Frontiers Metabolic reprogramming of the tumor immune microenvironment in ovarian cancer: A novel orientation for immunotherapy

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Description

While menadione (vitamin K3) is a created version of vitamin K, phylloquinone (vitamin K1) and menaquinones (vitamin K2, MK-n) are found naturally in food (57)

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doi: 10.3390/nu11092165 535 MirandaAMStelutiJFisbergRMMarchioniDM

These transporter might play essential roles in the sequestration of oxidized glutathione in vacuoles in situation of extreme oxidative stress (Queval et al., 2011) as described below