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4a , one of the initial hits, inhibited GSTO1 enzyme activity with a half-maximal inhibitory concentration (IC 50 ) value of 3.1 M

The hydrophobic tails embed themselves into the membrane, while hydrophilic head groups remain exposed on the surface, enabling stable and energy-independent anchoring of functional moieties [17]

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Similarly, NO inhibition showed a strong positive correlation with acetic acid, ABTS assay, and FRAP assay, reinforcing the link between antioxidant potential and NO inhibition