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Fluorescence lifetime images were acquired using a confocal laser-scanning microscope (Leica SP8)

10.1038/cr.2010.178 74 MorrisD.GuerraC.DonohueC.OhH.KhurasanyM.VenketaramanV

doi: 10.1186/s13024-017-0225-5 245 TuDGaoYYangRGuanTHongJ-SGaoH-M

Importantly, elevated inflammasome activation and aberrant oxidative stress response were both strongly correlated with worse clinical disease outcome, supporting the concept that myeloid-derived inflammatory responses are closely associated with disease severity in COVID-19

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