glutathione pathway and acetaminophen Illustration of the effects of on glutathione, GSH reduces NAPQI, the metabolite

GSH reduces NAPQI, the metabolite responsible for hepatotoxicity in acetaminophen toxicity. Toxic doses increase oxidation into NAPQI, overwhelming glutathione. How does ethanol interfere with acetaminophen metabolism? Image: https: t.co 6EY9dIwLXY Chronic acetaminophen ingestion resulting in severe anion gap metabolic acidosis secondary to 5 oxoproline accumulation: an under diagnosed phenomenon BMJ Case Reports 5 Oxoprolinuria as a Cause for Metabolic Acidosis Renal Fellow Network Clinically relevant therapeutic approaches against acetaminophen hepatotoxicity and acute liver failure ScienceDirect added a new Figure depicting the pathways of the metabolism of acetaminophen (paracetamol) to the Ethanol Metabolism page: https: themedicalbiochemistrypage.org ethanol metabolism.php

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