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In particular, Phe286 6.58 and Phe290 6.62 , located at the entrance of the ligand-binding pocket, are thought to contribute to the accessibility of the acyl-modified peptide through their hydrophobic properties (You et al., 2023)

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Whereas heteroplasmic mtDNA single nucleotide variants (SNVs) tend to be somatic in origin and to accumulate with age, we find that heteroplasmic indels tend to be quantitatively maternally inherited, with their relative levels influenced by nuclear genetic variation

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