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fermentum can improve memory and cognitive function in AD models (Kesika et al., 2021), as shown in Table 2

Mitochondria-derived cell-to-cell communication

In the mouse heart, USP1 expression is markedly higher than the other BMAL1 deubiquitinases, USP2 and USP9X , while in the hypothalamus USP9X was much higher than the others ( USP1 playing a dominant role in cardiac circadian regulation

Diabetic nephropathy (DN), referring to the deterioration of kidney function associated to both Type 1 and Type 2 diabetes, can progress to chronic kidney disease and, in fact, is a strong predictor of mortality in diabetic patients