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10.3389/fphar.2019.00753 163

Quantified fluorescence intensity measurements are shown in Fig

Cas13b is a type VI-B CRISPR-associated RNA-guided RNase differentially regulated by accessory proteins Csx27 and Csx28

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Based on overall rates of missense variation [71, 72], we might expect every individual to carry roughly 510 missense alleles in these enzymes on average