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Predicting tumor cell line response to drug pairs with deep learning

Thus, preincubation with the glutathione inhibitor buthionine sulfoximine (BSO) induced massive cell death, whereas N -acetyl cysteine, a precursor of glutathione synthesis, improved the resistance to cisplatin treatment

A systematic search was conducted across Medline (Ovid), Embase, and Web of Science from inception to January 2025 to identify relevant literature on oxidative stress, mitochondrial dysfunction, and antioxidant therapies in fibromyalgia (FM)

The resulting complex can regulate gene activity by binding directly to DNA regulatory elements called estrogen response elements (EREs), leading to the recruitment of additional factors involved in the regulation of transcription (207)

This research aims to assess their potential role as a method for metabolic deprogramming and improve our understanding of the mechanisms involved in the anti-obesity action of this medicinal plant