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Role of microglia in CNS inflammation

Inflammopharmacology (2022) 30:45363

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This toxic effluent can damage pulmonary vasculature and alveoli (leading to acute lung injury), constrict renal vessels and harm tubular epithelium (causing acute kidney injury), alter myocardial electrophysiology and contractility (inducing cardiac dysfunction), promote hepatocyte death (disrupting liver metabolism), and compromise the blood-brain barrier (resulting in cerebral edema and neuronal damage)