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Microglia and beyond: innate immune cells as regulators of brain development and behavioral function

Similar content being viewed by others Introduction Increased prevalence of obesity has led to a tsunami of metabolic diseases such as type 2 diabetes mellitus, dyslipidemia, and nonalcoholic fatty liver disease (NAFLD) 1

Carbon tetrachloride, 36,37 acetaminophen, 38 allyl alcohol, 39 ethanol, 40 and others have been suggested to involve LPO-induced cell death, with an essential role for iron

Notably, excessive iron overload acts as a key driver of ferroptosis, a unique form of regulated cell death

92 Endoplasmic reticulum stress treatment mainly improves the symptoms of UC by regulating endoplasmic reticulum function and reducing the abnormal accumulation of intracellular proteins, thereby inhibiting the inflammatory response of cells