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Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases

The autoimmune performance of HT is based on the interaction between environmental factors and genetic susceptibility [9], but its specific pathogenesis has not been clarified

Lastly, a new diagnostic algorithm [H 2 FPEF score(Reddy et al., 2018)] that defines the most relevant clinical features (obesity, hypertension, atrial fibrillation, pulmonary hypertension, aging and diastolic dysfunction) of HFpEF has been recently developed (Figure 1)