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HGH (Somatropin): FDA-approved for specific indications: pediatric growth hormone deficiency, adult GHD, Turner syndrome, HIV/AIDS-related wasting, short bowel syndrome Prescription-only medication requiring physician monitoring Illegal to distribute for off-label purposes including anti-aging (per the 1990 Anabolic Steroids Control Act amendments) Brand names include Genotropin, Norditropin, Humatrope, Saizen CJC-1295 and Ipamorelin: Neither is FDA-approved for any therapeutic indication Available as research compounds for laboratory use only (RUO Research Use Only) Not scheduled substances, but not approved for human therapeutic use Ipamorelin has undergone Phase I/II clinical trials (Johansen et al., 1999) but development did not progress to approval For a deeper look at Ipamorelin's regulatory history, see our Ipamorelin FDA approval status guide

In fact, most of these herbs are considered adaptogens - a family of plants and herbs that have a balancing effect on the hypothalamic-pituitary-endocrine axis which influences multiple pathways in your body involved with fatigue

Anyone considering the use of retatrutide, tesamorelin, or any combination of unlicensed or investigational agents for weight management or body composition purposes should seek medical advice before proceeding