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Fatty liver congestion caused increased free radicals and oxidative stress, which led to depleted glutathione

Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple negative breast cancer cells

122 (18), 1459414678 (2022) A

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When Burnet first learnt of the technique he declared it would become 'the most powerful weapon in antibody formation studies.' Other immunologists were equally impressed by the simplicity of the method with Edwin Lennox describing it as 'experimental brilliance and analytical thinking in the finest combination' (Marks)