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Yaikwawong and colleagues (Yaikwawong et al., 2025) reported in a 12-month randomized controlled trial in 78 patients with T2D and MASLD that 1,500 mg/day curcumin significantly reduced TNF-, IL-1, IL-6, and malondialdehyde levels at all follow-up intervals (3, 6, 9, and 12 months) while increasing antioxidant enzyme activities (glutathione peroxidase, superoxide dismutase) and significantly improving hepatic steatosis and liver stiffness measured by FibroScan

Mining the high-resolution proteome data of Wititkornkul et al