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doi: 10.1016/j.ejphar.2024.176399 169 AbazaNMEl-MallahRMShaabanAMobasherSAAl-HassaneinKFAbdel ZaherAAet al

[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Park S.M., Oh Y.H., Lim G.H., An J.H., Lee J.H., Gwag B.J., Won S.J., Seo K.W., Youn H.Y

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The condition crops up often among adolescents, with up to 80% experiencing the skin bumps many simply outgrow it by the time they become adults

The alanine at position 2 of the peptide was substituted with Aminoisobuturic acid (Aib) to protect the molecule from DDP-IV inactivation, and a lactam bridge was introduced between amino acids 16 and 20 to stabilize the secondary structure to ensure glucagon receptor potency