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81 Notably, Wnt5a, a common nonclassical Wnt pathway activator, after secretion by fibroblasts, activates the classic Wnt signalling pathway in AT2 cells and inhibits the transdifferentiation of AXIN2 + AT2 cells with stem cell activity into AT1 cells, thus maintaining the dryness of AT2 cells

It has been shown to upregulate genes associated with DNA repair and antioxidant defense while simultaneously downregulating genes linked to inflammation and cellular senescence (aging)

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This is pivotal in regeneration as a healthy vascular network brings necessary blood flow containing healing elements to different systems in the body.2 BPC 157 produces beneficial effects by blocking a molecule that inhibits growth and healing