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Influence of extracellular acidosis on matrix protein homeostasis in tumour cells and fibroblasts

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Flow cytometry for ROS and apoptosis assays HCC cells were seeded and treated with vehicle control, sorafenib, NAC/GSH combine with Sorafenib for 48 h

The lack of efficacious pharmacological methods for treating CIPN and preventing its development makes CIPN-related neuropathic pain a serious therapeutic gap in current medicine and pharmacotherapy