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typical therapeutic doses are well below the toxic threshold and are considered safe

Pharmacol Biochem Behav 98(1):161168 Miura H et al (2011) Long-lasting effects of inescapable-predator stress on brain tryptophan metabolism and the behavior of juvenile mice

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PARP-1 contributes to this dysregulation by depleting NAD+ and interfering with SIRT1 activity, which is essential for AMPK activation (59)

(2002), the risk for the development of secondary delusional ideation was significantly higher in those with lower ToM task scores, suggesting that better mentalizing capacities may provide a protective barrier against the development of delusional explanations of unusual perceptual experiences (Bartels-Velthuis et al., In another study, Clemmensen et al