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Thymosins were discovered in the mid 1960s, when Allan Goldstein from the Laboratory of Abraham White at the Albert Einstein College of Medicine in New York studied the role of the thymus in development of the vertebrate immune system

Further, except GPx1, the roles of other seleno-GPxs (GPx2, GPx3, GPx4, and GPx6) in the cellular radiosensitivity/resistance are scarcely investigated