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Proteomic and metabolomic analysis can help characterize the molecular composition and metabolites of natural ingredients

doi: 10.1016/j.pathophys.2006.05.007

10.1111/jcmm.12618 417 ZhangQ.KongW.ZhuT.ZhuG.ZhuJ.KongX.et al (2022)

McCoy and colleagues reported that 5-day treatment of dissociated rat hippocampal neurons with Dihexa increased dendritic spine density approximately three-fold compared to vehicle control (~41 spines per 50 m of dendrite versus ~15 spines), with the increase reflecting both new spine formation and increased spine-head width consistent with synaptic maturation [2]