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Here we report two cases of metastatic malignant gastrointestinal tumors where severe immune-mediated hepatotoxicity (IMH) developed, characterized by liver failure, after the ICI therapy

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These enzyme complexes act to incorporate an atom of oxygen into nonactivated hydrocarbons, which can result in either the introduction of hydroxyl groups or N-, O- and S-dealkylation of substrates

Chemosphere Peng Y, Zhang C, Gong X et al (2020) Transformation of nitrogen during microalgae liquefaction in subcritical/supercritical ethanol

Specifically, genomic instability characteristic of many cancers including GBM elicit engagement of the cyclic guanosine monophosphate (GMP) adenosine monophosphate (AMP) synthase (cGAS)- stimulator of IFN genes (STING) pathway which prompts secretion of type one interferon (IFN) into the TME [154, 155]