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Here are some general guidelines: Mild Deficiency: For those with a mild deficiency, a typical dosage might be 1,000 micrograms (mcg) once a week for several weeks

Research using kinetic analysis of isotope experiments with tracer doses of radioactive vitamin B12 has shown that the biological half-life of vitamin B12 in plasma is approximately 6 days

Many patients come in just for B12 without any other treatment