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Rejuvenation Res 2006

Studies have shown that both classical and trans IL-6 signals can trigger STAT3 phosphorylation and activate the JAK/STAT3 pathway in a time-dependent manner (224)

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In a salicylate-induced tinnitus rat model, chronic systemic salicylate administration significantly upregulated BDNF expression and CREB phosphorylation in the AC, accompanied by ultrastructural synaptic changes (Yi et al., 2018)

To exclude the possibility that IL18R1 binds as a result of the formation of the CXCL10CXCR3 complex, we did comparative co-IP and quantification among CXCL10, CXCR3, and IL18R1