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Iron is imported via endocytosis of Fe 3+ -loaded Tf, or via DMT1 for non-transferrin-bound iron (NTBI), and the zinc transporter protein, SLC39A14, and stored in the labile iron pool (LIP) or as ferritin [23]

doi: 10.3389/fenvs.2014.00053 31 DatJ.VandenabeeleS.VranovE.Van MontaguM.Inz*D.Van BreusegemF

Although astrocytes can utilize fatty acids as an alternative energy source, prolonged reliance on lipid oxidation results in oxidative stress and mitochondrial impairment, exacerbating neurodegeneration 82