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doi: 10.31491/apt.2020.03.014

Dual regulation of gluconeogenesis by insulin and glucose in the proximal tubules of the kidney

Studies involving approximately 900 participants consistently demonstrated fat loss without changes in IGF-1, preserved glucose homeostasis despite fat reduction, absence of anabolic tissue growth effects, and safety profile comparable to placebo

doi: 10.1038/ejcn.2014.46

Check the vial upon arrival: if the powder appears as a cohesive white or off-white cake at the bottom of the vial with no discoloration or moisture, it's safe to store at 20C and use as normal