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Pathogenic bacteria such as Fusobacterium nucleatum , Parvimonas micra , Peptostreptococcus anaerobius , and Solobacterium moorei are enriched, while beneficial bacteria like Streptococcus thermophilus and Lactobacillus gallinarum are depleted [116]

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The administration of the peptide achieves the onset of stage 2 sleep, as well as the non-REM phase when the muscles are maximally relaxed, and there are no sudden body movements

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Raw mutation data were converted into Mutation Annotation Format (MAF) files and analyzed using the online tool OmicStudio ( to generate oncoplot 47